Nucleus® MSR Upright Fluorescence Microscopes Configurator

Your selection will determine your system’s compatibility with either Olympus, Zeiss, or Nikon objectives. The optical performance of all systems is equivalent. Objective lenses are not included.

The Zeiss ICS optical system has an optional eyepiece module. This module cannot be used if a junction block is selected.

The optional eyepiece module includes both a C-mount camera port as well as binocular eyepieces. A manual switch allows the user to divert the image-forming either to the camera or the eyepieces. The light is diverted either 100% to the camera or 100% to the eyepieces - both can not be used simultaneously.

For more information on optical system selection, please refer to our article.

The epi-illuminator provides high intensity light matching the excitation wavelengths of many common fluorophores. Epi-fluorescence imaging requires the appropriate filter sets mounted in Zeiss "Push & Click" filter cubes. These must be purchased separately.

To use a third party light source for epi-illumination, select the MLG3A. For additional information on epi-illumination, please refer to our article.

The MLL low profile transmitted illuminator provides basic transmitted illumination for Nucleus upright microscopes. A simple collector and diffuser design provides high intensity and uniformity for basic bright-field imaging tasks where a condenser is not required. SM1 threading in front of the lens elements supports installation of a 25mm filter.

By default, the MSR system uses a software autofocus. Adding on an HL04 hardware autofocus improves the scanning speed in certain scenarios.

For a full explanation of the difference between laser (hardware) autofocus and camera (software) autofocus, see our autofocus methods compared article.

The optional junction block provides an additional injection port in infinity space between the filter cube turret and the objective. This option is not available with the laser autofocus option, as that already takes up the additional injection port.

Please note: While most other Nucleus microscope modules can be user-installed, junction block installation must be carried out by Zaber. For more information on the junction block, please refer to our article.

Maximize your walk-away time by selecting an X-MOR-E motorized objective changer. The objective turret allows for automated switching between up to 4 objectives.

For additional information on the objective changer, please refer to our article.

While optional, the X-JOY3 controller is a highly recommended companion module for the MSR microscope. It provides precise and intuitive control over sample positioning, saving you time during setup and simplifying system use.

The MSR supports any standard C-mount camera and any adaptors that mount onto the standard C-mount interface.

Our standard camera option is the CC01, a FLIR Blackfly camera featuring Sony’s IMX249 2.3 MP monochrome sensor (colour sensor available). It is an extremely cost effective introductory camera which can provide a starting point for identifying your performance requirements. It offers outstanding value for low light imaging applications such as multi-channel fluorescence, with a quantum efficiency of 70% at 525 nm and a 13 mm diagonal sensor area. A high speed USB 3.1 connection (included) provides frame rates up to 41 FPS.

For more information on camera selection and compatibility, please refer to our article. For non-standard camera mounting, scroll down to contact our engineering team for customizations.

The MSR assembly is designed to be mounted onto a standard M6/25mm optical table. Zaber offers an optional mounting baseplate for the smaller XY stage configurations designed to keep your system compact.

To maximize stiffness, we recommend mounting the MTR upright microscope tower and XY stage to a honeycomb core optical breadboard or table that is at least 50 mm thick. For larger XY stages (ASR205 and ASR305), the MSR must be mounted onto an optical table. The minimum size required depends on the XY stage chosen as shown in the table below: