Automated Fluorescence Microscopy Platform & Subsystems
Key Features
- Publication-Ready Images.
Capture clear and detailed epifluorescence, brightfield and phase contrast images using industry-standard Zeiss, Nikon, or Olympus optics. - Breakthrough Speed & Maximum Walk-Away Time.
Accurately scan 96 well plates in 3.8 seconds at 5X magnification or scan up to 6 microplates at once. - Modular Design with Online Configurator Tool.
Build your system in just a few clicks. The Nucleus online configuration tool guides you through module selection and displays pricing at each step. - Low Up-Front Cost.
Starting price for a standalone system is $26,000. The platform's open architecture ensures no hidden costs of proprietary consumables or mandatory software licenses.
Breakthrough
Speed
Compact
(29 x 29 x 26 cm)
Laser Autofocus Module
User-Friendly
Software & API
Industrial
Reliability
Shipping in
Under 2 Weeks
High Production
Capacity
The Nucleus® microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular imaging.
For OEMs and system integrators, Nucleus reduces time-to-market by providing a single platform from prototyping to production, all while enabling the capture of clear, actionable images at the quality and speed your customers demand.
For lab managers, Nucleus can significantly improve productivity and walk-away time with its speed, industrial reliability, and affordability.
Nucleus® MVR inverted fluorescence microscopes
Starting Price
$26,345 (USD)
Representative Image
- Compact and configurable inverted microscope
- Motorized XY movement, focus, and filter cube changes allow fully automated whole slide imaging and well plate scanning
- Linear motor focus stage provides 20 nm minimum incremental move, 200 nm repeatability and zero backlash
- Available with XY stage travel up to 305 mm
Nucleus® MSR upright fluorescence microscopes
Starting Price
$26,576 (USD)
Representative Image
- Configurable upright microscope with adjustable height to accommodate large samples and custom illumination
- Motorized XY movement, focus, and filter cube changes allow fully automated whole slide imaging and well plate scanning
- Linear motor focus stage provides 20 nm minimum incremental move, 200 nm repeatability and zero backlash
- Available with XY stage travel up to 305 mm
Nucleus® MKR fluorescence microscope cores
Starting Price
$13,950 (USD)
Representative Image
- Microscope core module with itegrated X-FCR filter cube turret, X-LDA linear motor focus stage and objective mount
- Holds 6 Zeiss "Push & Click" style filter cubes
- 350 ms adjacent optic change time
- 20 nm minimum incremental focus adjustment
Nucleus® HL04 Laser Autofocus Sensor
Starting Price
$8,900 (USD)
Representative Image
- Low-power 785 nm IR laser is safe for live cells
- Supports a wide range of standard objectives from Zeiss, Nikon, Olympus and Edmund Optics
- Fast, accurate and reliable autofocus for Nucleus® microscopes
Nucleus® MLT transmitted light illuminators
Starting Price
$4,461 (USD)
Representative Image
- Single LED transmitted light illuminator
- High intensity white LED provides broad spectrum illumination
- Supports both brightfield and phase contrast imaging
- Shutter and intensity can be controlled by µManager miscoscopy software
X-ADR-AE Series — Linear Motor XY Microscope Stages
Starting Price
$10,552 (USD)
Representative Image
- A Nucleus microscopy module
- Linear motors for high speed quiet XY operation
- 130 x 100 mm, 250 x 100 mm travel
- 1 nm resolution linear encoder for direct position measurement and correction
X-ASR-E Series — Closed-loop Motorized XY Scanning Stages with Built-in Controllers and Motor Encoders
Starting Price
$5,536 (USD)
Representative Image
- Includes Nucleus microscopy modules
- 50 x 50 mm - 305 x 305 mm travel
- Built-in controller or motor-only models
- Motor encoder for slip/stall detection and automatic recovery
Nucleus® X-MOR-E objective turrets
Starting Price
$4,117 (USD)
Representative Image
- High-speed focus achieved by moving a single objective rather than the whole turret
- Highly repeatable and secure magnetic alignment delivers consistent results in demanding high-content screening applications
- Holds 4 objectives (Zeiss ICS, Nikon CFI60, Olympus)
Nucleus® X-FCR filter cube turrets
Starting Price
$6,070 (USD)
Representative Image
- Holds 6 Zeiss "Push & Click" style filter cubes
- 350 ms adjacent optic change time
- Supported by µManager open source microscopy software
Nucleus® MLR reflected light iIlluminators
Starting Price
$3,426 (USD)
Representative Image
- 3 LED epifluorescence illuminator
- 2 available LED configuration provides excitation for common fluorophores including DAPI, GFP, Cy3, FITC, TRITC, TxRed, Cy5 (MLR3B)
- Supports epifluorescence, reflected brightfield and reflected darkfield imaging modes
- Shutter and intensity can be controlled by µManager miscoscopy software
Nucleus® X-LCA4 4-channel LED controllers
Starting Price
$1,456 (USD)
Representative Image
- Drives 4 LEDs at up to 3 A per channel with extremely stable output
- Rapid LED channel switching maximizes throughput of multi-channel imaging
- Manual control knobs for quick adjustment of illumination channels
- Automatic detection and configuration for Zaber LED illuminators
Motorized filter wheels with built-in controllers and motor encoders
Starting Price
$2,932 (USD)
Representative Image
- Interchangeable filter holders for 25 mm optics (10 positions) or 32 mm optics (7 positions)
- Smooth, high speed filter changes; adjacent filter change time of 57 ms (10 position wheel)
- Optional IO; 1 digital input, 2 digital outputs
- Mounting provided for optical cage systems and C-mount components