Automated Microscope Platform & Subsystems

- High Performance Imaging for Maximum Throughput
Capture clear, detailed images at breakthrough speeds. Combine industry-standard Zeiss, Nikon, Olympus, and Mitutoyo optics with rapid automation to maximize your throughput. Supports 3rd party confocal, SIM and FRAP modules. - Easy, Intuitive Automation
Automate complex imaging tasks with ease. Get started instantly with Zaber’s free, user-friendly software and API, or integrate seamlessly with popular 3rd-party microscopy platforms. - Low Up-Front Cost
Starting price for a standalone system is under $30,000. The platform's open architecture ensures no hidden costs of proprietary consumables or mandatory software licenses. - Interchangeable Modules for Custom Setups
Configure unique systems using a wide range of standard modules. Swap modules as you transition from R&D to production. Customizations available with fast turnaround times.
The Nucleus® microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular imaging.
For OEMs and system integrators, Nucleus reduces time-to-market by providing a single platform from prototyping to production, all while enabling the capture of clear, actionable images at the quality and speed your customers demand.
- Shorten time to market while delivering high speed, high quality systems.
- Accelerate R&D by starting with a stand-alone automated microscope.
- Seamlessly transition to a highly optimized and production-ready optical subsystem.
- Interchangeable modules with a common software interface makes reconfiguring systems for additional projects quick and easy.
- Custom modules are also available upon request.
- Customize for speed (scan a microplate in 3.8 seconds) or capacity (scan 6 microplates at once).
- Build your bespoke microscope with Zaber's online configuration tools.
- With a starting price of $30k, parallel systems multiply your productivity.
- No hidden costs of proprietary consumables or mandatory software licenses.
Microscope Configurators
X-ADR-AE Series — Linear Motor XY Microscope Stages
Starting Price
$10,763 (USD)

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- 130 x 100 mm or 250 x 100 mm travel options
- 1 nm resolution linear encoders provide 5 µm accuracy, 500 nm repeatability, and 50 nm minimum incremental move
- Ultra quiet linear motors provide 750 mm/s top speed and are maintenance free
- Built-in controller saves space and simplifies cable management. Easily connect via USB and daisy chain to other Zaber products
ASR Series — Motorized XY Microscope Stages
Starting Price
$5,647 (USD)

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- 50 x 50 mm - 305 x 305 mm travel
- Built-in controller or motor-only models
- Motor encoder for slip/stall detection and automatic recovery
- Includes Nucleus microscopy modules
Nucleus® X-FCR filter cube turrets
Starting Price
$6,191 (USD)

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- Holds up to 6 Zeiss push & click type filter cubes
- Motorized turret with built-in controller allows filter cube changes in 350 ms
- Daisy-chains with other Zaber devices for control through a single USB connection
- µManager support allows seamless integration of X-FCR and X-LCA4 LED controller, synchronizing cube changes and LED channel switching
Nucleus® X-LCA4 4-channel LED controllers
Starting Price
$1,485 (USD)

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- Drives 4 LEDs at up to 3 A per LED with extremely stable output
- Each LED channel can be controlled independently through a USB connection that can be daisy chained with any Zaber X-Series devices
- LED functions can be controlled via Zaber Launcher or µManager open source microscopy software
- 4 TTL-compatible digital inputs and 2 TTL-compatible digital outputs allow low latency, independent on/off control of all 4 channels
Nucleus® MLR reflected light Illuminators
Starting Price
$3,495 (USD)

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- 3 LED lamp channels, with customizable lamp combinations
- Provides excitation for common fluorophores including DAPI, GFP, Cy3, FITC, TRITC, TxRed, Cy5 (MLR3B)
- µManager controllable intensity and shutter
- Manual control knobs on X-LCA4 controller allow for quick manual adjustment in addition to computer control
Nucleus® MKR fluorescence microscope cores
Starting Price
$14,229 (USD)

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- Modular microscope core includes X-FCR motorized filter cube turret and X-LDA linear motor focus stage
- Innovative magnetic quick-change objective system allows the objective to be changed in seconds and supports any objective thread
- Filter cube turret accepts six Zeiss "push & click" style filter cubes
- Optional MJB junction block (sold separately) provides an additional optical path that joins the main optical path between the objective lens and the filter cube
Nucleus® MLT transmitted light illuminators
Starting Price
$3,150 (USD)

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- Single high intensity white LED lamp provides broad spectrum illumination
- Includes long working distance condenser with adjustable aperture stop
- Allows brightfield and phase contrast observation modes
- µManager controllable intensity and shutter
Nucleus® X-MOR-E objective turrets
Starting Price
$4,199 (USD)

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- High-speed focus achieved by moving a single objective rather than the whole turret
- Highly repeatable and secure magnetic alignment delivers consistent results in demanding high-content screening applications
- Holds 4 objectives (Zeiss ICS, Nikon CFI60, Olympus)
- Select the X-MOR-E in our Microscope Configurator to price and order a complete microscope
Nucleus® HL04 Laser Autofocus Sensor
Starting Price
$9,078 (USD)

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- Maximize throughput with fast, reliable autofocus
- Focus hold mode for long duration imaging and XY scanning.
- Unrestricted objective selection with full compatibility for Nikon, Zeiss, Olympus and Edmund Optics objectives
- Simple and intuitive control through the free Zaber Launcher software, and Zaber Motion Library API.


