Automated Microscope Platform & Subsystems

Nucleus Microscope from Zaber
  • High Performance Imaging for Maximum Throughput
    Capture clear, detailed images at breakthrough speeds. Combine industry-standard Zeiss, Nikon, Olympus, and Mitutoyo optics with rapid automation to maximize your throughput. Supports 3rd party confocal, SIM and FRAP modules.
  • Easy, Intuitive Automation
    Automate complex imaging tasks with ease. Get started instantly with Zaber’s free, user-friendly software and API, or integrate seamlessly with popular 3rd-party microscopy platforms.
  • Low Up-Front Cost
    Starting price for a standalone system is under $30,000. The platform's open architecture ensures no hidden costs of proprietary consumables or mandatory software licenses.
  • Interchangeable Modules for Custom Setups
    Configure unique systems using a wide range of standard modules. Swap modules as you transition from R&D to production. Customizations available with fast turnaround times.

The Nucleus® microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular imaging.

For OEMs and system integrators, Nucleus reduces time-to-market by providing a single platform from prototyping to production, all while enabling the capture of clear, actionable images at the quality and speed your customers demand.

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X-ADR-AE Series — Linear Motor XY Microscope Stages

Starting Price
$10,763 (USD)

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  • 130 x 100 mm or 250 x 100 mm travel options
  • 1 nm resolution linear encoders provide 5 µm accuracy, 500 nm repeatability, and 50 nm minimum incremental move
  • Ultra quiet linear motors provide 750 mm/s top speed and are maintenance free
  • Built-in controller saves space and simplifies cable management. Easily connect via USB and daisy chain to other Zaber products
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ASR Series — Motorized XY Microscope Stages

Starting Price
$5,647 (USD)

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  • 50 x 50 mm - 305 x 305 mm travel
  • Built-in controller or motor-only models
  • Motor encoder for slip/stall detection and automatic recovery
  • Includes Nucleus microscopy modules
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Nucleus® X-FCR filter cube turrets

Starting Price
$6,191 (USD)

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  • Holds up to 6 Zeiss push & click type filter cubes
  • Motorized turret with built-in controller allows filter cube changes in 350 ms
  • Daisy-chains with other Zaber devices for control through a single USB connection
  • µManager support allows seamless integration of X-FCR and X-LCA4 LED controller, synchronizing cube changes and LED channel switching
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Nucleus® X-LCA4 4-channel LED controllers

Starting Price
$1,485 (USD)

X-LCA4 Nucleus® X-LCA4 4-channel LED controller

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  • Drives 4 LEDs at up to 3 A per LED with extremely stable output
  • Each LED channel can be controlled independently through a USB connection that can be daisy chained with any Zaber X-Series devices
  • LED functions can be controlled via Zaber Launcher or µManager open source microscopy software
  • 4 TTL-compatible digital inputs and 2 TTL-compatible digital outputs allow low latency, independent on/off control of all 4 channels
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Nucleus® MLR reflected light Illuminators

Starting Price
$3,495 (USD)

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  • 3 LED lamp channels, with customizable lamp combinations
  • Provides excitation for common fluorophores including DAPI, GFP, Cy3, FITC, TRITC, TxRed, Cy5 (MLR3B)
  • µManager controllable intensity and shutter
  • Manual control knobs on X-LCA4 controller allow for quick manual adjustment in addition to computer control
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Nucleus® MKR fluorescence microscope cores

Starting Price
$14,229 (USD)

MKR025A Microscope Core

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  • Modular microscope core includes X-FCR motorized filter cube turret and X-LDA linear motor focus stage
  • Innovative magnetic quick-change objective system allows the objective to be changed in seconds and supports any objective thread
  • Filter cube turret accepts six Zeiss "push & click" style filter cubes
  • Optional MJB junction block (sold separately) provides an additional optical path that joins the main optical path between the objective lens and the filter cube
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Nucleus® MLT transmitted light illuminators

Starting Price
$3,150 (USD)

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  • Single high intensity white LED lamp provides broad spectrum illumination
  • Includes long working distance condenser with adjustable aperture stop
  • Allows brightfield and phase contrast observation modes
  • µManager controllable intensity and shutter
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Nucleus® X-MOR-E objective turrets

Starting Price
$4,199 (USD)

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  • High-speed focus achieved by moving a single objective rather than the whole turret
  • Highly repeatable and secure magnetic alignment delivers consistent results in demanding high-content screening applications
  • Holds 4 objectives (Zeiss ICS, Nikon CFI60, Olympus)
  • Select the X-MOR-E in our Microscope Configurator to price and order a complete microscope
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Nucleus® HL04 Laser Autofocus Sensor

Starting Price
$9,078 (USD)

HL04 laser autofocus module on Zaber Nucleus microscope.

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  • Maximize throughput with fast, reliable autofocus
  • Focus hold mode for long duration imaging and XY scanning.
  • Unrestricted objective selection with full compatibility for Nikon, Zeiss, Olympus and Edmund Optics objectives
  • Simple and intuitive control through the free Zaber Launcher software, and Zaber Motion Library API.
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