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Nucleus® HL04 Laser Autofocus Sensor

About This Series

Zaber's HL04 Laser Autofocus Sensor adds a reliable and fast autofocus system to Zaber Nucleus® microscopes and MKR microscope cores. The low power 785 nm infrared laser avoids photobleaching and is safe for live cell imaging. Single point and continuous scanning modes support high throughput imaging with area scan and line scan TDI cameras. The HL04 sensor integrates directly with the focus drive of an Nucleus® MKR microscope core to achieve low latency control for rapid and accurate focus.

Achieve excellent long-term stability support during long duration studies with active compensation for thermal drift. High repeatability ensures consistent results in multi-dimensional imaging protocols.

Configuration and control are easy using Zaber Launcher’s free microscope app, while the Zaber Motion Library API supports more advanced automation.

When mounted to a Zaber Nucleus® microscope, the MJB25C-F1 junction block provides the required input into the optical path of the system and includes a pre-mounted 785nm notch filter.

The HL04 autofocus sensor is not intended for use on its own or with third party systems. To function, it must be used as part of a Nucleus microscope system.

HL04 laser autofocus module on Zaber Nucleus microscope.
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  1. Direct communication with focus stage for high-speed focus operation tracking.
  2. Low energy 785 nm IR laser is safe for live cell imaging.
  3. Compatible with the objectives of your choice from Nikon, Zeiss, Olympus and Edmund Optics
  4. Easy and intuitive control via Zaber Launcher software and Zaber Motion Library API
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Easy Set-Up

Zaber's devices can share both data and power through a daisy-chain, which reduces cabling and makes set-up as easy as 1, 2, 3:

  1. Connect the Zaber device to your computer via USB or RS-232 port.
  2. Connect the power supply to your Zaber device.
  3. Send instructions or automate your set-up using the Zaber Launcher.
Photo instructions of Typical Daisy-Chaining

For more details on daisy-chaining, read our technical article, "Daisy-chaining Data and Power to Reduce Cabling", or to determine which accessories you need for your system, try our Connection Guide Tool.

For additional information about setting up our devices, please visit our Support page, which includes our Getting Started Guide, Troubleshooting Guides, product user manuals, and other resources.